Transmutation is focusing on the tumor transformation process from normal to malignant and invasive cells by acquisition of mutations. For us, it’s very important to show the clonal growth of the tumor (diverse transformed cells in a tumor have different aggressiveness) and its heterogeneous behavior. Having that in mind, we planned to use different textures and colors to represent the sequential levels of transformation and aggressivity of tumor cells.

OUR INSPIRATION has been the cell shape variation and increasing roughness along tumor progression. Transformed cells are identified by histology and their stronger/intensive staining in comparison with surrounding normal tissues/cells. This will be depicted by different color schemes.